Neural DSP’s Nano Cortex for dyed-in-the-wool analog advocates new to the concept, is a whole rig—digital amp, cabinet simulator, effects unit, and capture device—in a box. It’s also a 24-bit, 48k Hz audio interface that can be powered by a laptop or power bank via USB-C. We reviewed the Nano Cortex upon its release in 2024. Like any new release, it left some hardcore users wanting for certain features. Some users found the effects roster underwhelming. There were also limitations about where you could situate effects relative to an amp capture. With a raft of new effects and greater flexibility, though, Neural’s 2.0.0 update addresses many concerns of power users and casual adopters alike.